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Switch Bioworks launches first-in-class field trials for microbial fertilizer

Switch Bioworks, a biotechnology firm dedicated to sustainable agriculture, has announced the start of field trials for its innovative microbial fertilizer. It has been authorized by the U.S. Department of Agriculture (USDA) and the Environmental Protection Agency (EPA).

This novel fertilizer uses living microbes to directly pull nitrogen from the air and deliver it to crops. This offers a promising alternative to traditional chemical fertilizers that rely heavily on fossil fuels.

The upcoming trials focus on corn, the world’s most widely cultivated crop, and are conducted across multiple sites in the U.S. Midwest. Data collected will help optimize the company’s microbial discovery and engineering platform, which originated at Stanford University.

The goal is to test how reliably these microbes establish on plant roots and activate nitrogen production under real-world conditions.

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Conventional fertilizer production depends on fossil fuels and faces supply chain vulnerabilities, especially amid rising costs and geopolitical uncertainties. Switch’s microbial solution aims to reduce dependency on these fossil-based inputs by leveraging genetically engineered microbes that convert air nitrogen into ammonia, a key fertilizer component. This process is designed to fit seamlessly with existing planting practices, making adoption easier for farmers.

The move comes at a time of increasing concern over fertilizer costs and supply chain fragility. Recent federal initiatives emphasize the importance of domestic fertilizer production and supply resilience.

Tim Schnabel, CEO of Switch Bioworks, highlighted that their approach addresses a fundamental biological challenge: enabling microbes to first establish on roots before switching into fertilizer production mode, optimizing efficiency.

As the trials progress, they will provide critical insights to refine the product before commercialization. Industry experts see this as a significant step toward greener, more resilient agricultural practices that could help secure global food supplies and reduce environmental impact.

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